Bone tissue engineering with human stem cells
نویسندگان
چکیده
منابع مشابه
Adult Mesenchymal Stem Cells for Tissue Engineering
The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering...
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Congenital defects, trauma, and disease can compromise the integrity and functionality of the skeletal system to the extent requiring implantation of bone grafts. Engineering of viable bone substitutes that can be personalized to meet specific clinical needs represents a promising therapeutic alternative. The aim of our study was to evaluate the utility of human-induced pluripotent stem cells (...
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In extensive bone defects, tissue damage and hypoxia lead to cell death, resulting in slow and incomplete healing. Human embryonic stem cells (hESC) can give rise to all specialized lineages found in healthy bone and are therefore uniquely suited to aid regeneration of damaged bone. We show that the cultivation of hESC-derived mesenchymal progenitors on 3D osteoconductive scaffolds in bioreacto...
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Cells that make up the bodychr('39')s tissues are usually three-dimensional architecture, the threedimensional culture system enables cells to create natural and in vivo interactions which is an ideal environment for 3D (Three-dimensional) cell growth and issues such as exchange of similar food exchanges inside Capillary in living tissue. In tissue engineering discussion, cell scaffolding is hi...
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Stem cell research has obtained much prominence in recent years for its therapeutic potential in dealing with serious diseases, many of which are essentially incurable by routine therapies. Mesenchymal stem cells with pluripotency and immunomodulatory properties are suitable candidates for tissue engineering and regenerative medicine. Today, nanofibrous scaffolds are widely used in tissue en...
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ژورنال
عنوان ژورنال: Stem Cell Research & Therapy
سال: 2010
ISSN: 1757-6512
DOI: 10.1186/scrt10